The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 29, 2022
Filed:
Feb. 12, 2019
Applicant:
Codiak Biosciences, Inc., Cambridge, MA (US);
Inventors:
Sriram Sathyanarayanan, Lexington, MA (US);
Douglas E. Williams, Boston, MA (US);
Dalia Burzyn, Newton, MA (US);
Adam Thomas Boutin, Cambridge, MA (US);
Sushrut Kamerkar, Cambridge, MA (US);
Assignee:
CODIAK BIOSCIENCES, INC., Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 15/113 (2010.01); A61K 9/50 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1135 (2013.01); A61K 9/5068 (2013.01); C12N 15/113 (2013.01); A61K 45/06 (2013.01); C12N 2310/11 (2013.01); C12N 2310/321 (2013.01); C12N 2310/3515 (2013.01); C12N 2320/32 (2013.01);
Abstract
Disclosed herein are compositions and methods comprising extracellular vesicles comprising nucleic acid that target genes, leading to macrophage polarization of tumor associated macrophages. In certain embodiments, disclosed herein are methods and compositions for increasing macrophage polarization for the treatment of cancer.