The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 29, 2022
Filed:
Jul. 13, 2020
Applicant:
Duke University, Durham, NC (US);
Inventors:
Ashutosh Chilkoti, Durham, NC (US);
Stefan Zauscher, Durham, NC (US);
Lei Tang, Durham, NC (US);
Sonal Deshpande, Durham, NC (US);
Assignee:
Duke University, Durham, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C12N 15/115 (2010.01); A61K 31/7105 (2006.01); C12Q 1/68 (2018.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 31/7105 (2013.01); C12N 15/115 (2013.01); C12N 2310/16 (2013.01);
Abstract
Compositions and methods disclosed herein can help provide improved delivery of non-natural therapeutic nucleotides for the treatment of diseases such as cancer. An example composition includes an assembly of amphiphilic polynucleotides, where each amphiphilic polynucleotide includes an aptamer portion, a first nucleotide portion, and a second nucleotide portion.