The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 29, 2022
Filed:
Mar. 20, 2017
Applicant:
The Provost, Fellows and Scholars of the College of the Holy and Undivided Trinity of Queen Elizabeth Near Dublin, Dublin, IE;
Inventors:
Timothy Foster, Dublin, IE;
Judy Higgins, Dublin, IE;
Elisabet Josefsson, Gothenburg, SE;
Joan Geoghegan, Dublin, IE;
Andrej Tarkowski, Gavle, SE;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/31 (2006.01); C07K 16/12 (2006.01); A61K 39/085 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/31 (2013.01); A61K 39/085 (2013.01); C07K 16/1271 (2013.01); A61K 38/00 (2013.01); A61K 39/00 (2013.01); A61K 2039/545 (2013.01); A61K 2039/55566 (2013.01);
Abstract
The present invention is directed to improved microbial antigen vaccines, pharmaceutical compositions, immunogenic compositions and antibodies and their use in the treatment of microbial infections, particularly those of bacterial origin, including Staphylococcal origin. Ideally, the present invention is directed to a recombinant staphylococcal MSCRAMM or MSCRAMM-like proteins, or fragment thereof, with reduced binding to its host ligand, for use in therapy.