The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 29, 2022

Filed:

Apr. 22, 2022
Applicant:

South China Agricultural University, Guangdong, CN;

Inventors:

Wenbao Qi, Guangdong, CN;

Ming Liao, Guangdong, CN;

Yiqun Chen, Guangdong, CN;

Jiahao Zhang, Guangdong, CN;

Bo Li, Guangdong, CN;

Jinyu Huang, Guangdong, CN;

Huanan Li, Guangdong, CN;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/145 (2006.01); A61K 39/12 (2006.01); C12N 7/00 (2006.01); C07K 14/005 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); C12N 7/00 (2013.01); A61K 39/00 (2013.01); C12N 2760/16121 (2013.01); C12N 2760/16122 (2013.01); C12N 2760/16134 (2013.01); C12N 2760/16152 (2013.01);
Abstract

The present disclosure discloses a whole avian-origin reverse genetic system, a recombinant H5N2 subtype avian influenza virus, a vaccine containing the virus, and a preparation method and application thereof. The genome of the recombinant virus is comprised of a modified HA gene derived from a highly pathogenic H5N6 subtype avian influenza virus strain, as well as PB2, PB1, PA, NP, NA, M and NS genes derived from H5N2 subtype avian influenza D7 virus strain. The recombinant virus is a recombinant H5N2 avian influenza virus rescued from the D7 virus strain as a backbone, which is an avirulent virus strain with the original immunogenicity, and can maintain a high virus titer during the chick embryo culture process. The recombinant virus fully meets the biological safety requirements and has a good application prospect.


Find Patent Forward Citations

Qi, Wenbao. (2022). Whole avian-origin reverse genetic system and recombinant h5n2 subtype avian influenza virus, vaccine and uses thereof (U.S. Patent No. 11512117). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11512117

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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