The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 29, 2022

Filed:

Nov. 24, 2020
Applicant:

Amgen Inc., Thousand Oaks, CA (US);

Inventors:

Jennifer R. Allen, Newbury Park, CA (US);

Michela Beltrani, Verona, IT;

Matthew P. Bourbeau, Woodland Hills, CA (US);

Teodora P. Damyanova, Verona, IT;

Iain Lingard, Verona, IT;

Ana E. Minatti, Los Angeles, CA (US);

Paolo Vincetti, Verona, IT;

Assignee:

AMGEN INC., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 513/04 (2006.01); A61P 3/04 (2006.01); C07D 487/04 (2006.01); C07D 498/04 (2006.01);
U.S. Cl.
CPC ...
C07D 513/04 (2013.01); A61P 3/04 (2018.01); C07D 487/04 (2013.01); C07D 498/04 (2013.01);
Abstract

The present disclosure provides compounds useful for the inhibition of Delta-5 Desaturase ('D5D'). The compounds have a general Formula I wherein the variables of Formula I are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a metabolic or cardiovascular disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.


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