The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 29, 2022
Filed:
Mar. 12, 2021
Applicant:
Incyte Corporation, Wilmington, DE (US);
Inventors:
Zhongjiang Jia, Kennett Square, PA (US);
Wayne Han, West Chester, PA (US);
Yongchun Pan, Wilmington, DE (US);
Timothy Martin, Hockessin, DE (US);
Jiacheng Zhou, Newark, DE (US);
Qun Li, Newark, DE (US);
Assignee:
Incyte Corporation, Wilmington, DE (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/04 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
C07D 401/04 (2013.01); A61K 9/0053 (2013.01); C07B 2200/13 (2013.01);
Abstract
The present invention relates to processes and intermediates for preparing 3-(cyanomethyl)-3-(4-{[(1R,2S)-2-phenylcyclopropyl]amino}piperidin-1-yl)azetidine-1-sulfonamide, and salts and solid forms thereof, which selectively modulate demethylase. Particular embodiments contemplate compounds and disease indications amenable to treatment by modulation of lysine specific demethylase-1 (LSD1).