The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 29, 2022

Filed:

Nov. 20, 2018
Applicants:

Icahn School of Medicine AT Mount Sinai, New York, NY (US);

The United States Government As Represented BY the Department of Veterans Affairs, Washington, DC (US);

Inventors:

Michael Ohlmeyer, New York, NY (US);

Dongming Cai, New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 211/90 (2006.01); A61P 25/28 (2006.01);
U.S. Cl.
CPC ...
C07D 211/90 (2013.01); A61P 25/28 (2018.01);
Abstract

A genus of dihydropyridine chemical modulators of synaptojanin is disclosed. These modulators are selective inhibitors of synaptojanin 1 and may be used to treat cognitive impairment or traumatic brain injury, including promoting regeneration in cases of traumatic brain injury, or for treating neurodegenerative disorders.


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