The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 29, 2022

Filed:

Jul. 02, 2019
Applicants:

Basf SE, Ludwigshafen am Rhein, DE;

Basf Corporation, Florham Park, NJ (US);

The Regents of the University of California, Oakland, CA (US);

Inventors:

Martin Ernst, Heidelberg, DE;

Stephan Zuend, Fremont, CA (US);

Bo Su, Berkeley, CA (US);

Ala Bunescu, Cambridge, GB;

John F. Hartwig, Berkeley, CA (US);

Assignees:

BASF SE, Ludwigshafen am Rhein, DE;

BASF CORPORATION, Florham Park, NJ (US);

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 213/00 (2006.01);
U.S. Cl.
CPC ...
C07C 213/00 (2013.01);
Abstract

A process for the preparation of amino alcohols includes condensing a compound of Formula (II), a stereoisomer, a tautomer, or a salt thereof with a compound of Formula (IIIa) or Formula (IIIb), a stereoisomer, a tautomer, or a salt thereof to form a condensation product; hydroxylating or acyloxylating the condensation product in the presence of an oxidant to obtain a hydroxylation or acyloxylation product; and subjecting the hydroxylation or acyloxylation product to one or more subsequent reactions comprising a hydrolysis reaction, alcohol deprotection, an amino lysis reaction, or a combination of two or more thereof to obtain an amino alcohol of Formula (I).


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