The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 29, 2022

Filed:

Dec. 20, 2018
Applicant:

Imec Vzw, Leuven, BE;

Inventor:

Chengxun Liu, Kessel-lo, BE;

Assignee:

IMEC VZW, Leuven, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 21/00 (2006.01); B01L 3/00 (2006.01); G01N 21/01 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502715 (2013.01); B01L 3/502746 (2013.01); G01N 21/00 (2013.01); B01L 2200/027 (2013.01); B01L 2200/0605 (2013.01); B01L 2300/0627 (2013.01); B01L 2400/082 (2013.01); G01N 2021/0193 (2013.01);
Abstract

A method for detecting, sorting, purifying and characterizing objects of interest in a liquid sample. The method comprises preparing, in a preparation module ON) of a microfluidic router system, the liquid sample for processing. Preparing comprises transporting the sample through a microfluidic channel, and forwarding the prepared sample from an outlet of the preparation module into an inlet of a routing module. Forwarding comprises coupling a microfluidic flow between the outlet and the inlet to passively buffer against or actively compensate for variations in a flow rate of the prepared sample at the outlet, and diverting the objects of interest from the microfluidic flow. Forwarding the sample comprises sensing a flow characteristic of the sample in preparation, routing module, or in flow connection, and controlling a flow control element taking the sensed characteristic into account to compensate for a variation in the flow rate by a closed-loop flow control.


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