The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 29, 2022

Filed:

Nov. 29, 2021
Applicant:

Replicate Bioscience, Inc., San Diego, CA (US);

Inventors:

Nathaniel Stephen Wang, San Diego, CA (US);

Shigeki Joseph Miyake-Stoner, San Diego, CA (US);

Parinaz Aliahmad, San Diego, CA (US);

Assignee:

Replicate Bioscience, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 48/00 (2006.01); A61K 31/58 (2006.01); A61K 45/06 (2006.01); C07D 407/14 (2006.01); A61K 39/12 (2006.01); A61P 35/04 (2006.01); A61K 9/14 (2006.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
A61K 39/12 (2013.01); A61K 9/146 (2013.01); A61K 39/001106 (2018.08); A61P 35/04 (2018.01); B82Y 5/00 (2013.01);
Abstract

The present disclosure relates to the field of molecular virology, and particularly relates to nucleic acid molecules encoding a modified equine encephalitis virus viral genome or self-replicating RNA (srRNA) construct, pharmaceutical compositions containing the same, and the use of such nucleic acid molecules and compositions for production of desired products in cell cultures or in a living body. Also provided are methods for eliciting an immune response in a subject in need thereof, as well as methods for preventing and/or treating cancer.


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