The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 29, 2022

Filed:

Mar. 11, 2019
Applicant:

Yeditepe Universitesi, Istanbul, TR;

Inventors:

Fikrettin Sahin, Istanbul, TR;

Ezgi Kasikci, Istanbul, TR;

Esra Aydemir Coban, Istanbul, TR;

Assignee:

YEDITEPE UNIVERSITESI, Istanbul, TR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 33/22 (2006.01); A61P 35/00 (2006.01); A61K 31/155 (2006.01);
U.S. Cl.
CPC ...
A61K 33/22 (2013.01); A61K 31/155 (2013.01); A61P 35/00 (2018.01);
Abstract

The present invention relates to a chemotherapeutic agent comprising a combination of alexidine dihydrochloride and sodium pentaborate pentahydrate. The chemotherapeutic agent includes 2.9 mg alexidine dihydrochloride compound and 2.5 mg sodium pentaborate pentahydrate compound, and is obtained by adding 0.5 ml dimethylsulfoxide compound into the alexidine dihydrochloride compound. Upon injecting them to the media containing healthy cells and cancer cells, their effects on cell viability were observed. In accordance with the obtained results; it was observed that when alexidine dihydrochloride solution at concentrations not harming healthy cells is combined with sodium pentaborate pentahydrate, pancreatic cancer cell viability decreased 10% more compared to use of alexidine dihydrochloride alone, and it was realized that this combination can be used as a chemotherapeutic agent for treatment of pancreatic cancer.


Find Patent Forward Citations

Sahin, Fikrettin. (2022). Chemotherapeutic agent comprising combination of alexidine dihydrochloride and sodium pentaborate pentahydrate (U.S. Patent No. 11510943). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11510943

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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