The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 29, 2022

Filed:

Jul. 15, 2016
Applicant:

Marinomed Biotech Ag, Vienna, AT;

Inventors:

Andreas Grassauer, Vienna, AT;

Eva Prieschl-Grassauer, Vienna, AT;

Angelika Bodenteich, Steyregg-Plesching, AT;

Martina Morokutti-Kurz, Vienna, AT;

Sabine Nakowitsch, Vienna, AT;

Cornelia Kaintz, Vienna, AT;

Assignee:

MARINOMED BIOTECH AG, Korneuburg, AT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 8/60 (2006.01); A61K 9/107 (2006.01); A61K 47/26 (2006.01); A61K 47/18 (2017.01); A61K 8/42 (2006.01); A61K 47/10 (2017.01); A61K 47/46 (2006.01); A61K 8/9789 (2017.01); A61K 31/58 (2006.01); A61K 47/36 (2006.01); A61K 31/56 (2006.01); A61K 38/13 (2006.01); A61K 31/138 (2006.01); A61K 31/337 (2006.01); A61K 8/02 (2006.01); A61K 8/34 (2006.01); A61K 31/436 (2006.01); A61K 31/12 (2006.01); A61K 9/00 (2006.01); A61Q 19/00 (2006.01); A61K 8/67 (2006.01);
U.S. Cl.
CPC ...
A61K 8/604 (2013.01); A61K 8/0291 (2013.01); A61K 8/345 (2013.01); A61K 8/42 (2013.01); A61K 8/673 (2013.01); A61K 8/9789 (2017.08); A61K 9/006 (2013.01); A61K 9/007 (2013.01); A61K 9/0031 (2013.01); A61K 9/0034 (2013.01); A61K 9/0043 (2013.01); A61K 9/0048 (2013.01); A61K 9/1075 (2013.01); A61K 31/12 (2013.01); A61K 31/138 (2013.01); A61K 31/337 (2013.01); A61K 31/436 (2013.01); A61K 31/56 (2013.01); A61K 31/58 (2013.01); A61K 38/13 (2013.01); A61K 47/10 (2013.01); A61K 47/18 (2013.01); A61K 47/26 (2013.01); A61K 47/36 (2013.01); A61K 47/46 (2013.01); A61Q 19/00 (2013.01); A61K 2800/10 (2013.01); A61Q 19/005 (2013.01);
Abstract

A method of increasing the solubility of a water-insoluble or slightly water-soluble hydrophobic organic compound in an aqueous solvent includes adding a saponin component selected from escin, glycyrrhizin, andextract to the aqueous solvent in an amount sufficient to trigger the formation of micelles, wherein in a first step the hydrophobic organic compound is pre-dissolved in an organic solvent, and in a second step the organic solvent comprising the pre-dissolved compound is admixed to the aqueous solvent, whereby at least a part of the insoluble or slightly soluble hydrophobic organic compound gets solubilized and dissolved in the aqueous solvent, yielding an aqueous composition having an increased concentration of said organic compound dissolved therein. Also indicated are pharmaceutical or cosmetic compositions including a water-insoluble or slightly water-soluble organic compound dissolved in an aqueous solvent at substantially increased concentrations.


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