The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 22, 2022

Filed:

Sep. 12, 2019
Applicant:

Kite Pharma, Inc., Santa Monica, CA (US);

Inventors:

Jed Wiltzius, Woodland Hills, CA (US);

Ruben Alvarez Rodriguez, Los Angeles, CA (US);

Jonathan Belk, Lebanon, NJ (US);

Assignee:

Kite Pharma, Inc., Santa Monica, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 14/705 (2006.01); A61K 31/675 (2006.01); A61K 31/7076 (2006.01); A61K 31/7088 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); A61K 45/06 (2006.01); A61K 35/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2878 (2013.01); A61K 31/675 (2013.01); A61K 31/7076 (2013.01); A61K 31/7088 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); A61P 35/02 (2018.01); C07K 14/70521 (2013.01); A61K 35/00 (2013.01); C07K 2317/53 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2317/92 (2013.01); C07K 2319/03 (2013.01); C07K 2319/30 (2013.01); C07K 2319/33 (2013.01);
Abstract

The invention provides antibodies, antigen binding fragments thereof, chimeric antigen receptors (CARs), and engineered T cell receptors, polynucleotides encoding the same, and in vitro cells comprising the same. The polynucleotides, polypeptides, and in vitro cells described herein can be used in an engineered CAR T cell therapy for the treatment of a patient suffering from a cancer. In one embodiment, the polynucleotides, polypeptides, and in vitro cells described herein can be used for the treatment of multiple myeloma.


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