The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 22, 2022
Filed:
Apr. 24, 2020
Applicant:
Prindex S.r.l., Naples, IT;
Inventors:
Roberto Paterno, Naples, IT;
Mariarosaria Santillo, Naples, IT;
Vittorio Enrico Avvedimento, Caserta, IT;
Luigi Michele Pavone, Naples, IT;
Assignee:
PRINDEX S.R.L., Naples, IT;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/705 (2006.01); G01N 33/564 (2006.01); C07K 14/47 (2006.01); G01N 33/94 (2006.01); A61K 39/00 (2006.01); C07K 14/72 (2006.01); C07K 16/28 (2006.01); C07K 16/40 (2006.01); C12N 9/02 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70571 (2013.01); A61K 39/00 (2013.01); C07K 14/4713 (2013.01); C07K 14/705 (2013.01); C07K 14/723 (2013.01); C07K 16/286 (2013.01); C07K 16/40 (2013.01); C12N 9/0036 (2013.01); C12Y 106/03001 (2013.01); G01N 33/564 (2013.01); G01N 33/942 (2013.01); A61K 38/00 (2013.01); G01N 2333/70571 (2013.01); G01N 2333/90209 (2013.01); G01N 2800/285 (2013.01); G01N 2800/52 (2013.01);
Abstract
The serotonin receptor 5HT2A (5HT2aR) and membrane NADPH oxidases (NOX enzymes) are found to be a target of autoantibodies present in Multiple Sclerosis patients. The present invention refers to peptides comprised in the extracellular regions of the human 5HT2aR and/or NOXs for diagnosis and therapy of Multiple Sclerosis.