The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 22, 2022

Filed:

Jan. 28, 2021
Applicant:

Innate Tumor Immunity, Inc., Princeton, NJ (US);

Inventors:

Gary Glick, Ann Arbor, MI (US);

Shomir Ghosh, Brookline, MA (US);

Edward James Olhava, Newton, MA (US);

William R. Roush, Tequesta, FL (US);

Roger Jones, Martinsville, NJ (US);

Assignee:

Innate Tumor Immunity, Inc., Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7084 (2006.01); C07H 21/00 (2006.01); C07H 21/02 (2006.01); A61K 39/395 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07H 21/00 (2013.01); A61K 31/7084 (2013.01); A61K 39/3955 (2013.01); C07H 21/02 (2013.01); C07K 16/2818 (2013.01); A61K 2039/505 (2013.01);
Abstract

This disclosure features chemical entities (e.g., a compound that modulates (e.g., agonizes) Stimulator of Interferon Genes (STING), or a pharmaceutically acceptable salt, and/or hydrate, and/or cocrystal, and/or drug combination of the compound) that are useful, e.g., for treating a condition, disease or disorder in which a decrease or increase in STING activity (e.g., a decrease, e.g., a condition, disease or disorder associated with repressed or impaired STING signaling) contributes to the pathology and/or symptoms and/or progression of the condition, disease or disorder (e.g., cancer) in a subject (e.g., a human). This disclosure also features compositions as well as other methods of using and making the same.


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