The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 22, 2022
Filed:
Aug. 21, 2018
Microbiotix, Inc., Worcester, MA (US);
The Penn State Research Foundation, University Park, PA (US);
Zachary D. Aron, Acton, MA (US);
Steven M. Kwasny, Blackstone, MA (US);
Matthew C. Torhan, Worcester, MA (US);
Jay P. Barbor, Worcester, MA (US);
Steven C. Cardinale, Hopedale, MA (US);
Michelle M. Butler, Auburn, MA (US);
Timothy J. Opperman, Arlington, MA (US);
Kenneth C. Keiler, Boalsburg, PA (US);
MICROBIOTIX, INC., Worcester, MA (US);
THE PENN STATE RESEARCH FOUNDATION, University Park, PA (US);
Abstract
The present invention is related to the development of therapeutics and prophylactics for the treatment and/or prevention of bacterial infections in humans and other mammals. A new class of small molecules is disclosed that inhibits the bacterial trans-translation/ribosome rescue mechanism and thus blocks infection of host cells by bacteria. Also disclosed are methods of using the small molecule inhibitors in the treatment/prevention of bacterial infections.