The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 22, 2022

Filed:

Mar. 02, 2018
Applicant:

Linda Chia-hui Yu, Taipei, TW;

Inventors:

Ling-Wei Hsin, Taipei, TW;

Linda Chia-Hui Yu, Taipei, TW;

Tsung-Chun Lee, Taipei, TW;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 217/04 (2006.01); A61P 1/00 (2006.01); C07D 401/06 (2006.01);
U.S. Cl.
CPC ...
C07D 217/04 (2013.01); A61P 1/00 (2018.01); C07D 401/06 (2013.01);
Abstract

A series of 8-phenyl-isoquinoline derivatives (I) exhibit high binding affinity to 5-HTreceptor (5-HTR) and demonstrate potent antinociceptive activity in two animal models for Irritable Bowel Syndrome (IBS) by intraperitoneal injection (i.p.) or by oral administration (p.o.). These 5-HTreceptor antagonists are a new class of therapeutic agents for the treatment of IBS.


Find Patent Forward Citations

Hsin, Ling-Wei. (2022). 8-phenyl-isoquinolines and pharmaceutical composition thereof used in the treatment of irritable bowel syndrome (U.S. Patent No. 11505529). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11505529

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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