The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 22, 2022

Filed:

Jun. 23, 2017
Applicants:

Quanta Biodesign, Ltd., Plain City, OH (US);

University of Washington, Seattle, WA (US);

Inventors:

Paul D. Davis, Dublin, OH (US);

D. Scott Wilbur, Seattle, WA (US);

Assignees:

Quanta BioDesign, Ltd., Powell, OH (US);

University of Washington, Seattle, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); C07D 209/60 (2006.01); C07C 271/16 (2006.01); C07C 279/24 (2006.01); C07D 403/14 (2006.01); C07C 317/44 (2006.01); C07C 331/28 (2006.01); C07K 14/605 (2006.01); C07D 257/02 (2006.01); C07C 235/08 (2006.01); C07C 235/48 (2006.01); C07D 207/404 (2006.01); C07D 209/48 (2006.01); C07K 16/30 (2006.01); C07K 16/40 (2006.01); A61K 51/10 (2006.01);
U.S. Cl.
CPC ...
C07D 209/60 (2013.01); A61K 51/106 (2013.01); C07C 235/08 (2013.01); C07C 235/48 (2013.01); C07C 271/16 (2013.01); C07C 279/24 (2013.01); C07C 317/44 (2013.01); C07C 331/28 (2013.01); C07D 207/404 (2013.01); C07D 209/48 (2013.01); C07D 257/02 (2013.01); C07D 403/14 (2013.01); C07K 14/605 (2013.01); C07K 16/3069 (2013.01); C07K 16/40 (2013.01); C07C 2603/18 (2017.05);
Abstract

Disclosed are general and 'substantially pure' branched discrete polyethylene glycol constructs useful in attaching to a variety of biologically active groups, for example, preferential locators, as well as biologics like enzymes, for use in diagnostics, e.g. imaging, therapeutics, theranostics, and moieties specific for other applications. In its simplest intermediate state, a branched discrete polyethylene glycol construct is terminated at one end by a chemically reactive moiety, 'A', a group that is reactive with a biologic material that creates “A”, which is a biologically reactive group, connected throughto a branched core (BC) which has attached at least two dPEG-containing chains, indicated by the solid line,, having terminal groups, which can be charged, non-reactive or reactable moieties and containing between about 2 and 64 dPEG residues.


Find Patent Forward Citations

Loading…