The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 22, 2022
Filed:
Dec. 21, 2020
Applied Molecular Transport Inc., South San Francisco, CA (US);
Thomas Carl Hunter, Mountain View, CA (US);
Randall J. Mrsny, Los Altos Hills, CA (US);
Weijun Feng, Danville, CA (US);
Tahir Mahmood, Bulingame, CA (US);
Charles Olson, South San Francisco, CA (US);
Sally Postlethwaite, Redwood City, CA (US);
Applied Molecular Transport Inc., South San Francisco, CA (US);
Abstract
The present disclosure provides delivery constructs comprising a carrier coupled to a heterologous payload, wherein coupling of the carrier to the payload can result in transportation of the payload (e.g., a therapeutic payload) into and/or across intact polarized epithelial cells (e.g., epithelial cells of the gut of a mammal). The delivery construct can be part of a pharmaceutical composition that can be orally administered to a subject to provide for improved, effective therapies for treatment of, e.g., inflammatory diseases or autoimmune diseases.