The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 22, 2022

Filed:

Dec. 21, 2011
Applicants:

Torild Wickstrom, Oslo, NO;

Anders Svadberg, Oslo, NO;

Ole Kristian Hjelstuen, Oslo, NO;

Dag M Evje, Oslo, NO;

Liane Ochsenfeld, Oslo, NO;

Inventors:

Torild Wickstrom, Oslo, NO;

Anders Svadberg, Oslo, NO;

Ole Kristian Hjelstuen, Oslo, NO;

Dag M Evje, Oslo, NO;

Liane Ochsenfeld, Oslo, NO;

Assignee:

GE HEALTHCARE LIMITED, Buckinghamshire, GB;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/00 (2006.01); A61M 36/14 (2006.01); A61K 47/12 (2006.01); C07B 59/00 (2006.01); B01J 19/00 (2006.01); C01B 9/08 (2006.01); C07C 51/363 (2006.01); A61K 51/04 (2006.01);
U.S. Cl.
CPC ...
A61K 47/12 (2013.01); A61K 51/0406 (2013.01); B01J 19/00 (2013.01); C01B 9/08 (2013.01); C07B 59/00 (2013.01); C07B 59/001 (2013.01); C07C 51/363 (2013.01);
Abstract

The present invention provides a novel method for the preparation ofF-fluoride (F) for use in radiofluorination reactions. The method of the invention finds use especially in the preparation ofF-labelled positron emission tomography (PET) tracers. The method of the invention is particularly advantageous where bulk solutions are prepared and stored in prefilled vials rather than being freshly prepared on the day of synthesis. Also provided by the present invention is a radiofluorination reaction which comprises the method of the invention, as well as a cassette for use in carrying out the method of the invention and/or the radiofluorination method of the invention on an automated radiosynthesis apparatus.


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