The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 22, 2022
Filed:
May. 08, 2018
Applicant:
Gritstone Bio, Inc., Emeryville, CA (US);
Inventors:
Wade Blair, Gaithersburg, MD (US);
Karin Jooss, Emeryville, CA (US);
Amy Rachel Rappaport, Daly City, CA (US);
Ciaran Daniel Scallan, San Francisco, CA (US);
Leonid Gitlin, Foster City, CA (US);
Assignee:
GRITSTONE BIO, INC., Emeryville, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C12N 15/86 (2006.01); A61P 31/12 (2006.01); A61K 39/12 (2006.01); C07K 14/47 (2006.01); C07K 14/74 (2006.01);
U.S. Cl.
CPC ...
A61K 39/001191 (2018.08); A61K 39/001188 (2018.08); A61K 39/12 (2013.01); A61P 31/12 (2018.01); C07K 14/4748 (2013.01); C07K 14/70539 (2013.01); C12N 15/86 (2013.01); A61K 2039/53 (2013.01); A61K 2039/545 (2013.01); A61K 2039/585 (2013.01); A61K 2039/605 (2013.01); A61K 2039/6037 (2013.01); A61K 2039/70 (2013.01);
Abstract
Disclosed herein are alphavirus vectors that include neoantigen-encoding nucleic acid sequences derived from a tumor of a subject. Also disclosed are nucleotides, cells, and methods associated with the vectors including their use as vaccines.