The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 22, 2022
Filed:
Nov. 02, 2017
Applicant:
Crowpierce Technologies, Llc, Canton, GA (US);
Inventors:
George E. Pierce, Canton, GA (US);
Sidney A. Crow, Smyrna, GA (US);
Assignee:
CROWPIERCE TECHNOLOGIES, LLC, Canton, GA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/50 (2006.01); A61K 47/60 (2017.01); C12P 13/20 (2006.01); C12N 9/82 (2006.01);
U.S. Cl.
CPC ...
A61K 38/50 (2013.01); A61K 47/60 (2017.08); C12N 9/82 (2013.01); C12P 13/20 (2013.01); C12Y 305/01001 (2013.01);
Abstract
Disclosed herein is an endotoxin-free asparaginase enzyme. Also disclosed are methods of using the disclosed enzyme to treat subjects with a disease treatable by depletion of asparagine. For example, the disclosed endotoxin-free asparaginase enzyme is useful in the treatment or the manufacture of a medicament for use in the treatment of acute lymphoblastic leukemia (ALL) in both adults and children, as well as other conditions where asparagine depletion is expected to have a useful effect.