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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11504379 B1

PDFFull Text
Date of Patent:
Nov. 22, 2022

Filed:

Aug. 06, 2018

Amide compound, and pin1 inhibitor, therapeutic agent for inflammatory diseases and therapeutic agent for cancer that use the same

Applicants:

Hiroshima University, Higashihiroshima, JP;

Tokyo University of Pharmacy & Life Sciences, Hachioji, JP;

The University of Tokyo, Tokyo, JP;

Inventors:

Tomoichiro Asano, Hiroshima, JP;

Yusuke Nakatsu, Hiroshima, JP;

Hisanaka Ito, Hachioji, JP;

Takayoshi Okabe, Tokyo, JP;

Assignees:

Hiroshima University, Hiroshima, JP;

Tokyo University of Pharmacy & Life Sciences, Tokyo, JP;

The University of Tokyo, Tokyo, JP;

Attorneys:

Jeffrey I. Auerbach

Auerbach, LLC

Primary Examiner:

Sun Jae Yoo

Int. Cl.
CPC ...
C07C 275/36 (2006.01); C07C 275/28 (2006.01); C07C 275/38 (2006.01); C07C 233/46 (2006.01); C07C 233/63 (2006.01); C07C 233/51 (2006.01); C07C 233/87 (2006.01); C07C 271/22 (2006.01); C07C 235/40 (2006.01); C07D 209/88 (2006.01); C07D 209/82 (2006.01); C07D 215/02 (2006.01); C07D 295/195 (2006.01); C07D 233/24 (2006.01); C07D 265/38 (2006.01); A61P 3/04 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); A61K 45/06 (2006.01); A61K 31/216 (2006.01); A61K 31/473 (2006.01); A61K 31/198 (2006.01); A61K 31/538 (2006.01); A61K 31/404 (2006.01);
U.S. Cl.
CPC ...
A61K 31/538 (2013.01); A61K 31/198 (2013.01); A61K 31/216 (2013.01); A61K 31/404 (2013.01); A61K 31/473 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07C 233/46 (2013.01); C07C 233/51 (2013.01); C07C 275/28 (2013.01); C07D 209/88 (2013.01); C07D 215/02 (2013.01); C07D 295/195 (2013.01);
Abstract

The purpose of the invention is to develop, as drug-candidate compounds, a group of novel compounds having the activity of inhibiting functions of Pin1. The invention provides: a compound represented by formula (I) or a salt thereof; and a Pin1 inhibitor, a pharmaceutical composition, a therapeutic or prophylactic agent for inflammatory diseases, a therapeutic or prophylactic agent for cancer, and a therapeutic or prophylactic agent for adiposity that use said compound/salt.

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