The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 22, 2022
Filed:
Apr. 09, 2020
Applicant:
Trustees of Boston University, Boston, MA (US);
Inventors:
Bjoern Markus Reinhard, Brookline, MA (US);
Suryaram Gummuluru, Westwood, MA (US);
Assignee:
TRUSTEES OF BOSTON UNIVERSITY, Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61K 9/127 (2006.01); B82Y 5/00 (2011.01); A61B 5/055 (2006.01); G01N 33/50 (2006.01); A61K 47/69 (2017.01); A61K 47/61 (2017.01); A61K 47/54 (2017.01);
U.S. Cl.
CPC ...
A61K 9/5123 (2013.01); A61B 5/055 (2013.01); A61K 9/127 (2013.01); A61K 9/1271 (2013.01); A61K 9/1272 (2013.01); A61K 9/5115 (2013.01); A61K 9/5192 (2013.01); A61K 47/543 (2017.08); A61K 47/61 (2017.08); A61K 47/6911 (2017.08); A61K 47/6923 (2017.08); A61K 47/6929 (2017.08); B82Y 5/00 (2013.01); G01N 33/5005 (2013.01);
Abstract
Embodiments disclosed herein relates to ganglioside GM3-containing mixed lipids nanoparticles having an overall size between 60-100 nm, the making thereof and the uses. The nanoparticles selectively targeted to CD169+ expressing cells such as dendritic cells and macrophage. The nanoparticles are endocytosed by the CD169+ expressing cells.