The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 22, 2022

Filed:

Mar. 20, 2019
Applicants:

Bioinfra Life Science Inc., Seoul, KR;

Pacific System Co., Ltd., Incheon, KR;

Inventors:

Chui Woo Kim, Seoul, KR;

Dong Hee Park, Seoul, KR;

Jong Ho Won, Seoul, KR;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/127 (2006.01); A61K 41/00 (2020.01); B01F 23/80 (2022.01); B01F 23/41 (2022.01); B01F 101/22 (2022.01); A61K 47/42 (2017.01); A61K 47/10 (2017.01);
U.S. Cl.
CPC ...
A61K 9/1277 (2013.01); A61K 41/0047 (2013.01); A61K 47/10 (2013.01); A61K 47/42 (2013.01); B01F 23/4105 (2022.01); B01F 23/808 (2022.01); B01F 23/4143 (2022.01); B01F 2101/22 (2022.01);
Abstract

Provided are a method for preparing liposomes comprising ultrasound reactive microbubbles for drug delivery, comprising (a) a step of producing ultrasound reactive microbubbles comprising an inert gas therein and having a first shell formed on the outer surface thereof, followed by forming a uniform size distribution of the ultrasound reactive microbubbles through an extruder; and (b) a step of producing liposomes comprising the ultrasound reactive microbubbles distributed in a uniform size and a medicament therein and having a second shell formed on the outer surface thereof, followed by forming a uniform size distribution of the liposomes through an extruder; and a liposome using same.


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