The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 15, 2022
Filed:
Feb. 19, 2019
Bruker France Sas, Wissembourg, FR;
Eric Breynaert, Bever, BE;
Johan Martens, Huldenberg, BE;
Francis Taulelle, Leuven, BE;
Pieter Leo Hendrik Verlooy, Grimbergen, BE;
Jean-Max Tyburn, Wissembourg, FR;
James Kempf, Arlington, MA (US);
Other;
Abstract
A method of enhancing the nuclear spin polarization of target molecules () uses a hyperpolarized source material () that is co-confined with the target molecules () in a porous molecular matrix (). The matrix () may be a D4R-polysiloxane copolymer such as polyoligosiloxysilicone number two (PSS-2) that has recesses of an appropriate diameter. A source material (), such as parahydrogen, is transferred to the matrix () together with the target molecules (), and an external pressure is applied to force them into the recesses of the matrix (). The nano-confinement of the source material () and target molecules () together enables or enhances a transfer of spin polarization from the source material () to the target molecules (). When the target molecules () are removed from the matrix (), the enhanced spin polarization greatly enhances the signal strength of the target molecules () in any subsequent magnetic resonance measurement.