The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 15, 2022
Filed:
Dec. 28, 2018
Bio-rad Laboratories, Inc., Hercules, CA (US);
John F. Regan, San Mateo, CA (US);
Serge Saxonov, Oakland, CA (US);
Michael Y. Lucero, San Francisco, CA (US);
Benjamin J. Hindson, Livermore, CA (US);
Phillip Belgrader, Severna Park, MD (US);
Simant Dube, Kirkland, WA (US);
Austin P. So, Pleasanton, CA (US);
Jeffrey C. Mellen, San Francisco, CA (US);
Nicholas J. Heredia, Mountain House, CA (US);
Kevin D. Ness, Pleasanton, CA (US);
Billy W. Colston, Jr., San Ramon, CA (US);
Bio-Rad Laboratories, Inc., Hercules, CA (US);
Abstract
Method of haplotype analysis. In an exemplary method, an aqueous phase containing nucleic acid may be partitioned into a plurality of discrete volumes. At least one allele sequence may be amplified in the volumes from each of a first polymorphic locus and a second polymorphic locus that exhibit sequence variation in the nucleic acid. At least one measure of co-amplification of allele sequences from both loci in the same volumes may be determined. A haplotype of the first and second loci may be selected based on the at least one measure of co-amplification.