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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11499157 B1

PDFFull Text
Date of Patent:
Nov. 15, 2022

Filed:

Jan. 17, 2019

Immunomodulatory small hairpin rna molecules

Applicants:

Nanyang Technological University, Singapore, SG;

Agency for Science, Technology and Research, Singapore, SG;

Inventors:

Dahai Luo, Singapore, SG;

Katja Fink, Singapore, SG;

Hui Yee Yong, Singapore, SG;

Chin Yong Victor Ho, Singapore, SG;

Assignees:

Nanyang Technological University, Singapore, SG;

Agency for Science, Technology and Research, Singapore, SG;

Attorney:

Shackelford, Bowen, McKinley & Norton, LLP

Primary Examiner:

Amy H Bowman

Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/117 (2010.01); A61K 31/713 (2006.01); C12N 15/113 (2010.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C12N 15/117 (2013.01); A61K 31/713 (2013.01); C12N 15/113 (2013.01); A61K 45/06 (2013.01); C12N 2310/14 (2013.01); C12N 2310/17 (2013.01); C12N 2310/20 (2017.05); C12N 2310/531 (2013.01); C12N 2320/31 (2013.01);
Abstract

The present invention generally relates to specific immune-modulatory RNA species that have a small hairpin structure (shRNA), and that can bind to retinoic acid inducible gene I receptor (RIG-I). In particular, said RNA species comprise a nucleotide insertion to create a kink in the stem region. Also encompassed are compositions comprising such shRNA, for use as antiviral or anticancer medication, or as adjuvants in vaccine.

Find Patent Forward Citations

Luo, Dahai. (2022). Immunomodulatory small hairpin rna molecules (U.S. Patent No. 11499157). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11499157

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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