The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 15, 2022
Filed:
Apr. 25, 2018
Applicant:
Interoligo Corporation, Gyeonggi-do, KR;
Inventors:
Jung Hwan Lee, Gyeonggi-do, KR;
Jong In Kim, Seoul, KR;
Jong Hun Im, Seoul, KR;
Jong Ook Lee, Gyeonggi-do, KR;
Jin Woo Kim, Daejeon, KR;
Assignee:
INTEROLIGO CORPORATION, Gyeonggi-Do, KR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/115 (2010.01); A61K 47/60 (2017.01); A61K 51/04 (2006.01); G01N 33/533 (2006.01); G01N 33/534 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
C12N 15/115 (2013.01); A61K 47/60 (2017.08); A61K 51/0404 (2013.01); G01N 33/533 (2013.01); G01N 33/534 (2013.01); G01N 33/574 (2013.01);
Abstract
A composition for imaging a tumorous disease region includes a fluorescence- or radioactive isotope-labeled ERBB2 aptamer, wherein the ERBB2 aptamer labeled with a radioactive isotope or a fluorescent dye is used to image the tumorous disease region in vivo. The composition may include a labeled hybridized aptamer comprising an aptamer represented as formula 1 hybridized with a labeled-ODN represented as formula 2.