The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 15, 2022
Filed:
Apr. 10, 2018
Antisense targeting dynamin 2 and use for the treatment of centronuclear myopathies and neuropathies
Applicants:
Genethon, Evry, FR;
Universite D'evry-val-d'essonne, Evry, FR;
Inserm (Institut National DE LA Sante ET DE LA Recherche Medicale), Paris, FR;
Inventor:
Ana Maria Buj Bello, Paris, FR;
Assignees:
GENETHON, Evry, FR;
UNIVERSITE D'EVRY-VAL-D'ESSONNE, Evry, FR;
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), Paris, FR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61P 25/02 (2006.01); A61K 31/712 (2006.01); A61K 38/46 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1137 (2013.01); A61K 31/712 (2013.01); A61K 38/465 (2013.01); A61P 25/02 (2018.01); C12N 2310/11 (2013.01); C12N 2310/3233 (2013.01); C12N 2320/31 (2013.01);
Abstract
The present invention concerns the use of antisense oligonucleotides (AON) capable of inhibiting expression of dynamin 2, advantageously human dynamin 2, for use in the treatment of Charcot-Marie-Tooth disease (CMT) and centronuclear myopathies (CNM).