The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 15, 2022
Filed:
Jul. 11, 2018
Alexion Pharmaceuticals, Inc., New Haven, CT (US);
Bridget Puffer, South Weymouth, MA (US);
Julian Chandler, Guilford, CT (US);
Nimish Gera, Waltham, MA (US);
Douglas L. Sheridan, Branford, CT (US);
Siddharth Jindal, Hamden, CT (US);
Paul P. Tamburini, Kensington, CT (US);
Alexion Pharmaceuticals, Inc., Boston, MA (US);
Abstract
The disclosure provides engineered polypeptides that specifically bind to human complement component C5 and/or serum albumin. The disclosure also provides fusion proteins comprising such engineered polypeptides, wherein such fusion proteins may be multivalent and multi-specific fusion proteins. The disclosure further provides nucleic acid molecules that encode such engineered polypeptides or fusion proteins, and methods of making such engineered polypeptides or fusion proteins. The disclosure further provides pharmaceutical compositions that comprise such engineered polypeptides or fusion proteins, and methods of treatment using such engineered polypeptides or fusion proteins.