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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11498940 B1

PDFFull Text
Date of Patent:
Nov. 15, 2022

Filed:

Apr. 08, 2020

Neuroactive steroids, compositions, and uses thereof

Applicant:

Sage Therapeutics, Inc., Cambridge, MA (US);

Inventors:

Gabriel Martinez Botella, Wayland, MA (US);

Boyd L. Harrison, Princeton Junction, NJ (US);

Albert Jean Robichaud, Boston, MA (US);

Francesco G. Salituro, Marlborough, MA (US);

Robert Jason Herr, Voorheesville, NY (US);

Robert Borbo Kargbo, Guilderland, NY (US);

Assignee:

Sage Therapeutics, Inc., Cambridge, MA (US);

Attorneys:

Honigman LLP

Andrew N. Weber

Jonathan P. O'Brien

Primary Examiner:

Barbara P Badio

Int. Cl.
CPC ...
C07J 43/00 (2006.01); A61K 31/58 (2006.01); C07J 7/00 (2006.01); A61K 45/06 (2006.01); C07J 21/00 (2006.01); C07J 1/00 (2006.01); C07J 13/00 (2006.01);
U.S. Cl.
CPC ...
C07J 43/003 (2013.01); A61K 31/58 (2013.01); A61K 45/06 (2013.01); C07J 1/0059 (2013.01); C07J 7/002 (2013.01); C07J 7/007 (2013.01); C07J 7/0085 (2013.01); C07J 13/007 (2013.01); C07J 21/00 (2013.01); C07J 21/008 (2013.01);
Abstract

Described herein are neuroactive steroids of the Formula (I): or a pharmaceutically acceptable salt thereof; wherein -------, R, R, R, A and L are as defined herein. Such compounds are envisioned, in certain embodiments, to behave as GABA modulators. The present invention also provides pharmaceutical compositions comprising a compound of the present invention and methods of use and treatment, e.g., such for inducing sedation and/or anesthesia.

Find Patent Forward Citations

Martinez Botella, Gabriel. (2022). Neuroactive steroids, compositions, and uses thereof (U.S. Patent No. 11498940). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11498940

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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