The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 15, 2022
Filed:
Jan. 17, 2020
Ascentage Pharma (Suzhou) Co., Ltd., Suzhou, CN;
The Regents of the University of Michigan, Ann Arbor, MI (US);
Ascentage Pharma Group Corp Limited, Hong Kong, CN;
Jianyong Chen, Suzhou, CN;
Yunlong Zhou, Suzhou, CN;
Guozhi Tang, Suzhou, CN;
Chengzhe Wu, Suzhou, CN;
Leilei Zhao, Suzhou, CN;
Lingling Jiao, Suzhou, CN;
Binghua Sheng, Suzhou, CN;
Shaomeng Wang, Superior Township, MI (US);
Chao-Yie Yang, Ann Arbor, MI (US);
Hao Chen, Suzhou, CN;
Wenliang Hu, Suzhou, CN;
Yu Jing, Suzhou, CN;
ASCENTAGE PHARMA (SUZHOU) CO., LTD., Suzhou, CN;
THE REGENTS OF THE UNIVERSITY OF MICHIGAN, Ann Arbor, MI (US);
ASCENTAGE PHARMA GROUP CORP LIMITED, Hong Kong, CN;
Abstract
Provided are compounds represented by Formula (I-A) and the pharmaceutically acceptable salts and solvates thereof, wherein R, R, R, R, R, X, Y, Z, Z, W, and (aa) are as defined as set forth in the specification. Provided are also compounds of Formula (I-A) for use to treat a condition or disorder responsive to Mcl-1 inhibition such as cancer.