The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 15, 2022
Filed:
Apr. 07, 2017
Acea Therapeutics, Inc., San Diego, CA (US);
Hangzhou Acea Pharmaceutical Research Co., Ltd., Hangzhou, CN;
Zhejiang Acea Pharmaceuticals Co., Ltd, Quzhou, CN;
Long Mao, San Diego, CA (US);
Jia Liu, San Diego, CA (US);
Yile Chen, Hangzhou, CN;
Yuning Hua, Hangzhou, CN;
Kongen Dai, Hangzhou, CN;
Yimei Bao, Hangzhou, CN;
Bojie Weng, Hangzhou, CN;
Xi-aopeng Mo, Hangzhou, CN;
Jian Wu, Hangzhou, CN;
Xiao Xu, San Diego, CA (US);
Wanhong Xu, Hangzhou, CN;
Xiaobo Wang, San Diego, CA (US);
ACEA Therapeutics, Inc., San Diego, CA (US);
Hangzhou ACEA Pharmaceutical Research Co., Ltd., Hangzhou, CN;
Zhejiang ACEA Pharmaceuticals Co., Ltd., Quzhou, CN;
Abstract
The present invention relates to methods of making certain pyrrolopyrimidine derivatives, which are useful in the treatment of proliferation disorders and other diseases related to the dysregulation of kinase (such as, but not limited to, EGFR (including HER), Alk, PDGFR, BLK, BMX/ETK, BTK, FLT3(D835Y), ITK, JAK1, JAK2, JAK3, TEC and TXK) and/or the respective pathways, salts, polymorphs, and amorphous forms of said compounds, synthetic intermediates for preparing said compounds, and pharmaceutical compositions comprising said compounds and methods for making such compositions.