The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 15, 2022

Filed:

Dec. 20, 2019
Applicant:

Eisai R&d Management Co., Ltd., Tokyo, JP;

Inventors:

George Moniz, Cambridge, MA (US);

Kristen Sanders, Gilmanton, NH (US);

Arani Chanda, Andover, MA (US);

Kenshi Yoshida, Tsukuba, JP;

Ming-Hong Hao, Quincy, MA (US);

Dominic Reynolds, Stoneham, MA (US);

Sudeep Prajapati, Belmont, MA (US);

Anand Selvaraj, Boston, MA (US);

Takashi Satoh, Newton, MA (US);

John Wang, Andover, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/12 (2006.01); C07D 239/48 (2006.01); A61K 31/505 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); A61K 31/505 (2013.01); C07D 239/48 (2013.01);
Abstract

A number of crystalline forms of N-(2-((6-(3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-methylureido)pyrimidin-4-yl)amino)-5-(4-ethylpiperazin-1-y1)phenyl)acrylamide are provided. These include a crystalline free base form, a crystalline monohydrochloride salt form, a crystalline dihydrochloride salt form, and a crystalline ethanesulfonate salt form. Methods of making and using crystalline compounds are also provided.


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