The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 15, 2022
Filed:
Nov. 23, 2020
Applicant:
Forma Therapeutics, Inc., Watertown, MA (US);
Inventors:
Jian Lin, Acton, MA (US);
Anna Ericsson, Shrewsbury, MA (US);
Ann-Marie Campbell, Monroe, CT (US);
Gary Gustafson, Ridgefield, CT (US);
Zhongguo Wang, Lexington, MA (US);
R. Bruce Diebold, Waltham, MA (US);
Susan Ashwell, Carlisle, MA (US);
David R. Lancia, Jr., Boston, MA (US);
Justin Andrew Caravella, Cambridge, MA (US);
Wei Lu, Newton, MA (US);
Assignee:
FORMA Therapeutics, Inc., Watertown, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 471/04 (2006.01); A61P 35/00 (2006.01); A61K 31/47 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); A61P 35/00 (2018.01); C07D 401/14 (2013.01); C07D 471/04 (2013.01); A61K 31/47 (2013.01);
Abstract
The invention relates to inhibitors of mutant isocitrate dehydrogenase (mt-IDH) proteins with neomorphic activity useful in the treatment of cell-proliferation disorders and cancers, having the Formula: where A, U, W, W, W, R-R, and Rare described herein.