The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 15, 2022
Filed:
Aug. 03, 2020
Applicant:
Case Western Reserve University, Cleveland, OH (US);
Inventors:
Bradley T. Lang, Cleveland, OH (US);
Jared M. Cregg, Cleveland, OH (US);
Jerry Silver, Bay Village, OH (US);
Yi-Lan Weng, Baltimore, MD (US);
Assignee:
CASE WESTERN RESERVE UNIVERSITY, Cleveland, OH (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/42 (2017.01); A61P 25/16 (2006.01); A61P 25/28 (2006.01); A61K 9/00 (2006.01); A61K 38/16 (2006.01); A61K 47/64 (2017.01); A61K 38/17 (2006.01);
U.S. Cl.
CPC ...
A61K 47/42 (2013.01); A61K 9/0019 (2013.01); A61K 38/162 (2013.01); A61K 38/179 (2013.01); A61K 47/645 (2017.08); A61P 25/16 (2018.01); A61P 25/28 (2018.01); A61K 2121/00 (2013.01);
Abstract
A method of inhibiting and/or reducing the activity, signaling, and/or function of leukocyte-common antigen related (LAR) family of phosphatases in a cell of a subject induced by proteoglycans includes administering to the cell a therapeutic agent that inhibits one or more of catalytic activity, signaling, and function of the LAR family phosphatases without inhibiting binding to or activation the LAR family phosphatases by the proteoglycans.