The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 15, 2022

Filed:

Jul. 12, 2016
Applicant:

Universidade DE Santiago DE Compostela, Santiago de Compostela, ES;

Inventors:

Carlos Garcia Gonzalez, Santiago de Compostela, ES;

Luis A Diaz Gomez, Santiago de Compostela, ES;

Carmen Alvarez Lorenzo, Santiago de Compostela, ES;

Angel J Concheiro Nine, Santiago de Compostela, ES;

Assignee:

UNIVERSIDADE DE SANTIAGO DE COMPOSTELA, Santiago de Compostela, ES;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/34 (2017.01); A61K 47/36 (2006.01); A61K 47/26 (2006.01); A61L 27/18 (2006.01); C08L 3/02 (2006.01); C08L 67/04 (2006.01);
U.S. Cl.
CPC ...
A61K 47/34 (2013.01); A61K 47/26 (2013.01); A61K 47/36 (2013.01); A61L 27/18 (2013.01); C08L 3/02 (2013.01); C08L 67/04 (2013.01); C08L 2203/02 (2013.01);
Abstract

A system for administering biologically active substances produced by foaming techniques using compressed gases or supercritical fluids relates to a porous system containing biologically active substances. The system includes a polymer matrix of poly(D,L-lactic-co-glycolic acid) or a polymer mixture containing poly(D,L-lactic-co-glycolic acid) of an intrinsic viscosity of less than 0.5 dL/g with other biodegradable synthetic or semisynthetic polyesters, a release-regulating component (starch and derivatives), and at least one biologically active substance. The matrix is biodegradable with a solid or semisolid consistency and a homogeneous appearance. A method for producing these systems using foaming with compressed fluids, and the use for the production of implants and scaffolds having this system are also disclosed. Optionally, a porogenic agent can be used for the formation of macropores by thermal decomposition.


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