The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 15, 2022

Filed:

Dec. 18, 2018
Applicant:

The Governing Council of the University of Toronto, Toronto, CA;

Inventors:

Xiaoyu Wu, Toronto, CA;

Claudia Regina Gordijo, Toronto, CA;

Azhar Z. Abbasi, Milton, CA;

Preethy Prasad, Toronto, CA;

Mohammad Ali Amini, Toronto, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 41/00 (2020.01); A61K 9/14 (2006.01); C01G 45/02 (2006.01); A61K 9/51 (2006.01); A61K 33/32 (2006.01); A61K 47/32 (2006.01); A61K 47/34 (2017.01); A61K 47/42 (2017.01); A61N 5/10 (2006.01);
U.S. Cl.
CPC ...
A61K 41/0038 (2013.01); A61K 9/0019 (2013.01); A61K 9/14 (2013.01); A61K 9/5146 (2013.01); A61K 33/32 (2013.01); A61K 47/32 (2013.01); A61K 47/34 (2013.01); A61K 47/42 (2013.01); A61N 5/1001 (2013.01); C01G 45/02 (2013.01); A61K 9/5169 (2013.01); A61N 5/10 (2013.01); A61N 2005/1021 (2013.01); A61N 2005/1098 (2013.01); C01P 2002/72 (2013.01); C01P 2002/84 (2013.01); C01P 2004/04 (2013.01); C01P 2004/24 (2013.01); C01P 2004/64 (2013.01); C01P 2006/22 (2013.01);
Abstract

Disclosed herein are multifunctional nanoparticle compositions. The compositions can be useful for the treatment of cancer by enhancing the anti-tumor effectiveness of radiation directed to a tissue, cell or a tumor and the methods of use thereof. The multifunctional nanoparticle composition comprises a metal oxide nanoparticle core; a functional coating on the surface of the metal oxide nanoparticle core; and a matrix carrier in which the coated nanoparticle is embedded.


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