The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 15, 2022
Filed:
Jun. 22, 2021
Applicants:
Lentigen Technology, Inc., Gaithersburg, MD (US);
University of Colorado, Denver, CO (US);
Inventors:
Dina Schneider, Potomac, MD (US);
Boro Dropulic, Ellicott City, MD (US);
Terry James Fry, Denver, CO (US);
Assignees:
Lentigen Technology, Inc., Gaithersburg, MD (US);
The Regemts of the University of Colorado, Denver, CO (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/63 (2006.01); C12N 15/13 (2006.01); C07K 14/47 (2006.01); A61K 39/395 (2006.01); A61K 35/17 (2015.01); C07K 14/725 (2006.01); C07K 14/705 (2006.01); C07K 16/28 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/17 (2013.01); C07K 14/7051 (2013.01); C07K 14/70521 (2013.01); C07K 16/2803 (2013.01); A61K 38/00 (2013.01); C07K 2317/622 (2013.01); C07K 2319/03 (2013.01);
Abstract
Chimeric antigen receptors containing TSLPR-CD19 and TSLPR-CD22 antigen binding domains are disclosed. Nucleic acids, recombinant expression vectors, host cells, antigen binding fragments, and pharmaceutical compositions, relating to the chimeric antigen receptors are also disclosed. Methods of treating or preventing cancer in a subject, and methods of making chimeric antigen receptor T cells are also disclosed.