The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 15, 2022
Filed:
Oct. 23, 2018
Applicant:
Lunella Biotech, Inc., Ottawa, CA;
Inventors:
Michael P. Lisanti, Fulton, MD (US);
Federica Sotgia, Fulton, MD (US);
Assignee:
LUNELLA BIOTECH, INC., Ontario, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/525 (2006.01); A61P 35/00 (2006.01); A61K 31/03 (2006.01); A61K 31/14 (2006.01); A61K 31/155 (2006.01); A61K 31/201 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
A61K 31/525 (2013.01); A61K 31/03 (2013.01); A61K 31/14 (2013.01); A61K 31/155 (2013.01); A61K 31/201 (2013.01); A61P 35/00 (2018.01); G01N 33/5079 (2013.01);
Abstract
The present disclosure relates to compounds that bind to flavin-containing enzymes and inhibit mitochondrial function, referred to herein as mitoflavoscins. Methods of screening compounds for mitochondrial inhibition and anti-cancer properties are disclosed. Also described are methods of using mitoflavoscins to prevent or treat cancer, bacterial infections, and pathogenic yeast, as well as methods of using mitoflavoscins to provide anti-aging benefits. Specific mitoflavoscin compounds are also disclosed.