The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 15, 2022
Filed:
Jun. 10, 2017
Applicant:
The Trustees of Columbia University IN the City of New York, New York, NY (US);
Inventors:
Sinisa Vukelic, New York, NY (US);
Gerard A. Ateshian, New York, NY (US);
Assignee:
The Trustees of Columbia University in the City of New York, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01J 3/44 (2006.01); A61B 5/00 (2006.01); G01J 3/02 (2006.01);
U.S. Cl.
CPC ...
A61B 5/0075 (2013.01); A61B 5/4514 (2013.01); G01J 3/44 (2013.01); G01J 3/0218 (2013.01); G01J 3/0229 (2013.01);
Abstract
The present application discloses methods, devices, and systems for generating spatially-resolved quantification of cross-linking in cartilage based on Raman scattering of excitation light. The examples presented demonstrate that the method provides a discriminating power sufficient to distinguish early onset of osteo-arthritis even before a patient is symptomatic.