The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 08, 2022
Filed:
Dec. 09, 2016
Applicant:
Laboratory Corporation of America Holdings, Burlington, NC (US);
Inventors:
Paul Scott Eastman, South San Francisco, CA (US);
Eric Sasso, South San Francisco, CA (US);
Assignee:
Laboratory Corporation of America Holdings, Burlington, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/564 (2006.01); G01N 33/68 (2006.01); G16B 25/00 (2019.01); G16B 20/00 (2019.01); G16B 25/10 (2019.01); G16B 20/20 (2019.01); G16H 50/50 (2018.01);
U.S. Cl.
CPC ...
G01N 33/564 (2013.01); G01N 33/68 (2013.01); G16B 20/00 (2019.02); G16B 20/20 (2019.02); G16B 25/00 (2019.02); G16B 25/10 (2019.02); G16H 50/50 (2018.01); G01N 2800/102 (2013.01); G01N 2800/60 (2013.01);
Abstract
Biomarkers useful for diagnosing and assessing inflammatory disease activity, for prediction of risk for progressive spinal and joint damage, in particular for axial spondyloarthritis (axSpA) and ankylosing spondylitis (AS), and for generating a dataset are provided, along with kits for measuring expression of the biomarkers. The invention also provides predictive models, based on the biomarkers, as well as computer systems, and software embodiments of the models for scoring and optionally classifying samples.