The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 08, 2022
Filed:
Apr. 10, 2019
Applicants:
Istituti Fisioterapici Ospitalieri, Rome, IT;
Istituto Nazionale Tumori I.r.c.c.s. “fondazione G. Pascale”, Naples, IT;
Universita' Degli Studi Di Roma “la Sapienza”, Rome, IT;
Inventors:
Gennaro Ciliberto, Rome, IT;
Paolo Antonio Ascierto, Naples, IT;
Luigi Fattore, Naples, IT;
Gerardo Botti, Naples, IT;
Rita Mancini, Rome, IT;
Assignees:
ISTITUTI FISIOTERAPICI OSPITALIERI, Rome, IT;
ISTITUTO NAZIONALE TUMORI I.R.C.C.S. “FONDAZIONE G. PASCALE”, Naples, IT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6886 (2018.01); C12N 15/113 (2010.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); A61K 45/06 (2013.01); C12N 15/113 (2013.01); C12N 2310/141 (2013.01); C12N 2310/3231 (2013.01); C12N 2320/31 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/178 (2013.01);
Abstract
miRNAs for in vitro diagnosis of resistance of tumors to BRAF/MEK pathway (also named as MAPK 5 pathway) inhibiting drugs and for treatment of tumors which are treated with said drugs, such as melanoma, by stimulating or inhibiting the expression of down-regulated or up-regulated miRNAs, respectively.