The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 08, 2022
Filed:
Dec. 10, 2018
Applicant:
Sequenom, Inc., San Diego, CA (US);
Inventors:
Cosmin Deciu, San Diego, CA (US);
Zeljko Dzakula, San Diego, CA (US);
John Allen Tynan, San Diego, CA (US);
Grant Hogg, San Diego, CA (US);
Assignee:
Sequenom, Inc., San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/683 (2018.01); G16B 20/00 (2019.01); C12Q 1/6827 (2018.01); G16B 20/10 (2019.01); G16B 30/00 (2019.01); C12Q 1/6869 (2018.01); C12Q 1/6883 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/683 (2013.01); C12Q 1/6827 (2013.01); G16B 20/00 (2019.02); G16B 20/10 (2019.02); G16B 30/00 (2019.02); C12Q 1/6869 (2013.01); C12Q 1/6883 (2013.01); C12Q 2600/156 (2013.01);
Abstract
Provided herein are methods for determining fetal ploidy according to nucleic acid sequence reads. Nucleic acid sequence reads may be obtained from test sample nucleic acid comprising circulating cell-free nucleic acid from the blood of a pregnant female bearing a fetus. Fetal ploidy may be determined according to genomic section levels and a fraction of fetal nucleic acid in a test sample.