The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 08, 2022

Filed:

Feb. 28, 2018
Applicant:

University of Southern California, Los Angeles, CA (US);

Inventors:

Scott E. Fraser, Glendale, AZ (US);

Simon Restrepo, Culver City, CA (US);

Joseph P. Dunham, Glendale, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/682 (2018.01); C12Q 1/6834 (2018.01); C12Q 1/6841 (2018.01); C12N 15/11 (2006.01); G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/682 (2013.01); C12N 15/11 (2013.01); C12Q 1/6834 (2013.01); C12Q 1/6841 (2013.01); G01N 21/6428 (2013.01); C12N 2310/531 (2013.01); G01N 2021/6439 (2013.01);
Abstract

Described herein is a method to create dendritic biocompatible polymers from pairs of complementary dendritic nucleic acid monomers in a controlled manner, using polymerization triggers. The dendritic monomers are constituted of nucleic acids and an organic polymer capable of self-assembly. Each polymer contains approximately 200 dendrites that can be used to attach labels and constitute a biologically compatible signal amplification technology. Depending on the context this technology could be used to reveal the presence of a large variety of analytes such as specific nucleic acid molecules, small molecules, proteins, and peptides.


Find Patent Forward Citations

Loading…