The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 08, 2022
Filed:
Aug. 29, 2019
Applicant:
Shanghaitech University, Shanghai, CN;
Inventors:
Jia Liu, Shanghai, CN;
Biao Jiang, Shanghai, CN;
Peixiang Ma, Shanghai, CN;
Guang Yang, Shanghai, CN;
Assignee:
ShanghaiTech University, Shanghai, CN;
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/63 (2006.01); A61K 31/70 (2006.01); C12N 15/90 (2006.01); A61K 31/7088 (2006.01); A61K 38/16 (2006.01); A61K 38/46 (2006.01); A61K 38/50 (2006.01); C12N 7/00 (2006.01); A01K 67/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/902 (2013.01); A61K 31/7088 (2013.01); A61K 38/162 (2013.01); A61K 38/465 (2013.01); A61K 38/50 (2013.01); C12N 7/00 (2013.01); C12N 2795/14123 (2013.01); C12N 2795/14143 (2013.01);
Abstract
Provided are amino acid sequences capable of binding to and inhibiting a Cas protein's ability to bind to a nucleic acid molecule, thereby inhibiting the Cas protein's function in genome editing. Such Cas protein inhibitors, which can be comprised of a major coat protein (G8P), an extracellular region of the G8P (G8P), or a biological equivalent, are useful in improving the specificity of Cas protein-based genome editing procedures.