The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 08, 2022
Filed:
Oct. 13, 2017
Applicant:
European Molecular Biology Laboratory, Heidelberg, DE;
Inventors:
Edward Lemke, Mannheim, DE;
Ivana Nikic, Tübingen, DE;
Gemma Estrada Girona, Heidelberg, DE;
Christine Köhler, Forst, DE;
Assignee:
European Molecular Biology Laboratory, Heidelberg, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/00 (2006.01); C12P 21/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/93 (2013.01); C12P 21/00 (2013.01); C12Y 601/01026 (2013.01);
Abstract
The invention relates to archaeal pyrrolysyl tRNA synthetases lacking a nuclear localization signal and/or comprising a nuclear export signal. The invention also relates to polynucleotides encoding said pyrrolysyl tRNA synthetases, eukaryotic cells comprising said polynucleotide and tRNA acylated by the pyrrolysyl tRNA synthetase or a polynucleotide encoding such tRNA, methods utilizing said cells for preparing polypeptides comprising unnatural amino acid residues, and kits useful in said methods.