The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 08, 2022
Filed:
Apr. 11, 2019
Applicant:
Whitehead Institute for Biomedical Research, Cambridge, MA (US);
Inventors:
Lee Kim Swee, Heidelberg, DE;
Hidde L. Ploegh, Boston, MA (US);
Assignee:
Whitehead Institute for Biomedical Research, Cambridge, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/07 (2010.01); A61K 39/395 (2006.01); A61K 47/68 (2017.01); A61K 47/66 (2017.01); A61K 47/65 (2017.01); C12N 5/00 (2006.01); A61K 39/00 (2006.01); C12N 5/0783 (2010.01); C12N 9/50 (2006.01); C12N 9/52 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0006 (2013.01); A61K 39/0011 (2013.01); A61K 47/65 (2017.08); A61K 47/66 (2017.08); A61K 47/68 (2017.08); C12N 5/0636 (2013.01); C12N 5/0638 (2013.01); C12N 9/52 (2013.01); A61K 2039/5158 (2013.01); C12Y 304/2207 (2013.01);
Abstract
Non-genetically engineered mammalian cells modified by sortase-mediated conjugation of an agent thereto are provided. Methods of conjugating agents to non-genetically engineered mammalian cells using sortase are provided. Methods of using the cells, e.g., for diagnostic and/or therapeutic purposes, are provided.