The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 08, 2022

Filed:

Oct. 14, 2019
Applicant:

Novartis Ag, Basel, CH;

Inventors:

Verena Brand, Munich, DE;

Dominik Feuerbach, Müllheim, DE;

Fabrizio Gasparini, Lausen, CH;

Nathalie George, Village-Neuf, FR;

Eveline Schaadt, Oberhaching, DE;

Derya Shimshek, Loerrach, DE;

Honnappa Srinivas, Brugg, CH;

Markus Waldhuber, Munich, DE;

Rainer Wilcken, Basel, CH;

Assignee:

NOVARTIS AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61P 25/28 (2006.01); A61K 39/395 (2006.01); A61K 39/00 (2006.01); C12N 7/00 (2006.01); C12N 15/70 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2803 (2013.01); A61K 39/3955 (2013.01); A61P 25/28 (2018.01); C12N 7/00 (2013.01); C12N 15/70 (2013.01); A61K 2039/505 (2013.01); C07K 2317/55 (2013.01); C07K 2317/565 (2013.01); C07K 2317/75 (2013.01); C07K 2317/77 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01); C07K 2319/21 (2013.01); C12N 2750/14143 (2013.01);
Abstract

The present invention provides antibodies that bind to and stabilize human Triggering Receptor Expressed on Myeloid cells 2 (TREM2) protein and methods of using these antibodies.


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